D-Penicillamine Induced Degenerative Dermopathy in a Patient with Wilson Disease
نویسندگان
چکیده
منابع مشابه
A case of penicillamine-induced dermopathy.
INTRODUCTION We describe an interesting patient with penicillamine-induced dermopathy. CLINICAL PICTURE A 49-year-old woman presented with a 1-year history of recurrent haemorrhagic blisters, milia and purpura over both her elbows, while on long-term penicillamine therapy (1.5 g daily) for Wilson's disease. Histologically, dermal elastin fibres were markedly reduced in the affected areas, con...
متن کاملConcurrent massive breast enlargement, myasthenia gravis and dermopathy as manifestations of penicillamine toxicity in a Wilson's disease patient.
Penicillamine toxicity in Wilson's disease has been well reported but rarely seen now as newer agents are being used. We present a case who developed multiple rare complications of Penicillamine concurrently. Our patient is one of three siblings on Penicillamine, she was the only one who developed massive breast enlargement four months after commencing Penicillamine therapy, as well as dermatol...
متن کاملD-penicillamine-induced pemphigus vulgaris in a patient with scleroderma-rheumatoid arthritis overlap syndrome.
Andrea Szegedi, Péter Surányi, Gabriella Szücs, Mária Kiss, János Hunyadi and János Gaál Department of Dermatology, Medical and Health Science Center, University of Debrecen, Department of Rheumatology, Kenézy Gyula Hospital, Bartók B. str. 2-26, HU-4043 Debrecen, 3rd Department of Internal Medicine Medical and Health Science Center, University of Debrecen, Debrecen and Department of Dermatolog...
متن کاملD-Penicillamine induced myasthenia gravis.
Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigabilit...
متن کاملD-penicillamine Induced Myasthenia Gravis
Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
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ژورنال
عنوان ژورنال: Journal of the Portuguese Society of Dermatology and Venereology
سال: 2018
ISSN: 2182-2409,2182-2395
DOI: 10.29021/spdv.76.2.826